Intra uterine insemination or IUI is a treatment that was previously a popular option that was used extensively to treat couples with unexplained subfertility. The procedure involves using a fine catheter to place a prepared sample of sperm into the female partners uterus around the time of ovulation. It was commonly used in conjunction with medication to make the female partner ovulate (often 2 or more eggs per cycle) which was associated with multiple pregnancies. Due to the lack of evidence of significant improvement in pregnancy rates without producing multiple pregnancies due to producing multiple eggs, it is now not recommended as standard treatment for couples with unexplained infertility.
It is still recommended for use in conjunction with Donor sperm in a process known as Donor Insemination (DI) for couples where the male has no sperm, in single women and in same sex couples. When used with Donor sperm most cycles are initially offered without the need to take medication to stimulate the ovaries. At Cheshire Reproductive Medicine we provide both Donor insemination (see treatment with donor sperm), as well as offering IUI to couples who for moral or ethical reasons feel they cannot undergo treatment with In vitro fertilization (IVF) to achieve a pregnancy or for some couples who have previously had successful IUI treatment and wish further attempts at IUI for personal reasons.